For the second time in two weeks, a crash at a busy Route 309 intersection has sent victims to the hospital.

First responders were summoned Wednesday to a report of a car-truck crash with injuries about 3:45 p.m. near the intersection of Wyoming Street and Claremont Avenue.

The crash, which injured three, took place in front of Hometown Village Square shopping plaza.

According to those at the scene, a Kia SUV with two female occupants pulled out from the shopping plaza parking lot onto the four lane highway and was broadsided by a Biros Utilities Inc. truck which was traveling northbound and towing a flatbed trailer loaded with several portable toilets.

Two women in the vehicle were initially treated at the scene and then taken to St. Luke’s Hospital-Miners Campus by Ryan Township ambulance.

The driver of the truck refused treatment at the scene.

Both the truck and the car sustained substantial damage.

Removal was handled by Hope’s Collision and Towing, Tamaqua. A section of one northbound lane was closed for a short time.

Rush Township police are investigating.

The same location, just north of the intersection of Route 309 and 54, was the site of a car-motorcycle crash on August 20. In that collision, a motorist attempted to pull out onto Route 309 from Wyoming Street and was struck by the motorcycle.