Interstate 81 is anticipated to reopen in Schuylkill County Wednesday morning, two days after it was shut down by a mass casualty crash.

Trooper David Beohm, state police public information officer, tweeted Tuesday night that crews continue to remove vehicles. Police estimated Monday that 50 to 60 vehicles were involved. The northbound lane was closed between Exit 107 and 119.

“Construction work will need to be done once the road has been cleared,” he said.

The road will be opened after construction.

Beohm confirmed Tuesday morning that there were fatalities but said the number had yet to be determined.

The incident occurred at 10:38 a.m. Monday, during a whiteout caused by a snow squall.

At least 24 people were injured and taken to four area hospitals.